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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNNT2
All Species:
9.09
Human Site:
Y251
Identified Species:
20
UniProt:
P45379
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P45379
NP_000355.2
298
35924
Y251
K
E
L
W
Q
S
I
Y
N
L
E
A
E
K
F
Chimpanzee
Pan troglodytes
XP_001146358
298
35917
Y251
K
E
L
W
Q
S
I
Y
N
L
E
A
E
K
F
Rhesus Macaque
Macaca mulatta
XP_001098451
391
45049
H344
K
E
L
W
Q
S
I
H
N
L
E
A
E
K
F
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P50752
301
35807
H254
K
E
L
W
Q
S
I
H
N
L
E
A
E
K
F
Rat
Rattus norvegicus
P50753
299
35712
H252
K
E
L
W
Q
S
I
H
N
L
E
A
E
K
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520262
172
20669
Y130
N
M
L
H
F
G
G
Y
I
Q
K
Q
G
K
T
Chicken
Gallus gallus
P02642
302
35967
R252
K
E
L
W
Q
T
I
R
D
L
E
A
E
K
F
Frog
Xenopus laevis
NP_001086207
265
31916
Y218
K
E
L
T
D
W
M
Y
Q
L
E
S
E
K
F
Zebra Danio
Brachydanio rerio
XP_001334951
249
29461
M202
S
E
M
W
Q
W
M
M
Q
L
E
A
E
K
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P19351
397
47429
V209
Q
E
L
W
E
L
I
V
K
L
E
T
E
K
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27371
405
47023
V244
R
G
L
H
A
R
I
V
K
L
E
A
E
K
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
71.6
N.A.
N.A.
86
87.2
N.A.
52.3
73.5
60.7
57.3
N.A.
22.1
N.A.
23.2
N.A.
Protein Similarity:
100
99.6
74.1
N.A.
N.A.
92
92.6
N.A.
55
85
72.1
70.4
N.A.
39.2
N.A.
40.4
N.A.
P-Site Identity:
100
100
93.3
N.A.
N.A.
93.3
93.3
N.A.
20
80
60
60
N.A.
53.3
N.A.
46.6
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
26.6
93.3
73.3
73.3
N.A.
73.3
N.A.
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
0
0
0
73
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
82
0
0
10
0
0
0
0
0
91
0
91
0
0
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
73
% F
% Gly:
0
10
0
0
0
10
10
0
0
0
0
0
10
0
0
% G
% His:
0
0
0
19
0
0
0
28
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
73
0
10
0
0
0
0
0
0
% I
% Lys:
64
0
0
0
0
0
0
0
19
0
10
0
0
100
0
% K
% Leu:
0
0
91
0
0
10
0
0
0
91
0
0
0
0
0
% L
% Met:
0
10
10
0
0
0
19
10
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
46
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
0
0
0
64
0
0
0
19
10
0
10
0
0
0
% Q
% Arg:
10
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% R
% Ser:
10
0
0
0
0
46
0
0
0
0
0
10
0
0
0
% S
% Thr:
0
0
0
10
0
10
0
0
0
0
0
10
0
0
10
% T
% Val:
0
0
0
0
0
0
0
19
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
73
0
19
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
37
0
0
0
0
0
0
19
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _